Overview

Phantom limb pain is a real and often intense sensation of pain in a limb or part of a limb that has been amputated, whether due to surgery or an accident. The pain can vary in intensity and duration, lasting from seconds to days. In addition to phantom limb pain, individuals may experience two related phenomena:

  • Phantom sensations: These occur when the person feels that the amputated limb or extremity is still part of their body, without the presence of pain. For example, someone may feel as though they can still move a missing leg or arm, or may attempt to walk on an amputated leg, forgetting it is no longer there.
  • Residual limb pain: This type of pain is localized in the remaining part of the amputated limb, often referred to as the stump. It is usually caused by medical issues such as nerve damage or nerve entrapment, where the nerve is compressed. About 70% of people with limb loss experience residual limb pain.

Despite the challenges these conditions pose, there are management strategies available to help alleviate the discomfort and improve quality of life for those affected by limb loss and its associated pains.

Symptoms

Phantom pain symptoms can be temporary or persist for several days. In the initial six months following limb amputation, the severity and occurrence of pain tend to diminish. However, up to 80% of individuals may still experience phantom pain up to two years post-amputation.

The sensations associated with phantom pain can include:

  • A sensation of burning or soreness.
  • Feelings of being squeezed, pinched, or as if in a vice.
  • Experiences of itching or a tingling sensation.
  • Sensations of shooting pain or stabbing.
  • A pulsating or pounding feeling.
  • The sensation of the limb being twisted.

Make an appointment with your healthcare provider if you experience:

  • Infection symptoms, such fever or redness in the remaining leg.
  • Severe discomfort that makes it difficult to sleep or go about everyday tasks.

Causes

Residual limb pain, affecting the stump left after an amputation, can be caused by a variety of issues. These issues include bruising, bone infections (osteomyelitis) or the formation of bone spurs, nerve damage which leads to neuropathic pain, or inflammation resulting in neuroma. Additionally, poor blood circulation, the use of a prosthetic device that fits poorly, pressure injuries such as bedsores, and infections of the skin or wounds also contribute to discomfort and pain in the residual limb.

Risk factors

Phantom pain may occur to anybody who has had an amputation. Some patients discover that when they are not using their prosthetic device, the discomfort is severe.

The following conditions might trigger the phantom limb pain:

  • Angina or chest pain.
  • Changes in the barometric pressure or temperature.
  • Constipation.
  • Herpes zoster (shingles).
  • Physical contact or sex.
  • Cigarette smoking.
  • Stress.

Diagnosis

To exclude infections and other possible causes of ongoing limb discomfort, your healthcare provider will conduct a physical examination and may suggest diagnostic tests. These examinations could involve imaging scans like ultrasounds and blood tests. If the source of the pain cannot be determined, based on your symptoms, your healthcare provider may diagnose phantom pain.

Treatment

The objective of phantom limb pain treatment is to reduce symptoms. Among them includes:

  • Antidepressants.
  • Antiseizure medications.
  • Beta blockers.
  • Muscle relaxers.
  • Nonsteroidal anti-inflammatory drugs (NSAIDs)
  • Pain relievers.

Pain treatments that include electrical impulses being sent to the brain, spinal cord, or nerves may be helpful. Among them are includes neurostimulation, spinal cord stimulation, and transcutaneous electrical nerve stimulation (TENS).

According to research, mirror therapy has shown promise in alleviating phantom pain. In this therapy, individuals typically spend approximately 20 minutes each day engaging in mobility exercises while observing the reflection of their intact limb in a mirror. This visual illusion tricks the brain into perceiving the presence of two healthy limbs.

Over time, the brain incorporates this visual feedback, potentially leading to a reduction in pain. Repeating the exercises may be necessary for sustained relief. The absence of pain in the phantom limb is attributed to the brain’s perception of the missing limb as non-existent. Working with a physical therapist can aid in mastering these exercises.

The following alternative treatment may also relieve phantom pain:

  • Acupuncture.
  • Biofeedback.
  • Massage.
  • Meditation or mindfulness exercises.

Doctors who treat this condition