Untreated Hepatitis Can Progress and Lead to Liver Cancer

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Liver Cancer

Viral Hepatitis is a viral infection that causes inflammation and damage to liver cells. It can occur in both acute and chronic forms. Without proper treatment, it may lead to liver failure, cirrhosis, or liver cancer. The disease often presents with mild or unclear symptoms, so many people are unaware they are infected. Regularly monitoring your health and watching for abnormal symptoms is therefore important.

Types of Viral Hepatitis

There are five types of viral hepatitis: A, B, C, D, and E. Each differs in modes of transmission, severity, and prevention, as outlined below.

Hepatitis A (HAV)

Transmission: Contaminated food and water; contact with an infected person’s feces

Severity: Not chronic; most cases resolve on their own

Warning signs: Fever, fatigue, nausea, jaundice (yellowing of the skin and eyes)

Prevention:

  1. Drink boiled or clean water; eat well-cooked food
  2. Wash your hands before meals
  3. Vaccination is available and highly safe and effective

Hepatitis B (HBV)

Transmission:

  1. Blood and body fluids, such as those from unprotected sex
  2. Sharing needles (e.g., among people who inject drugs)
  3. Needle-stick injuries in healthcare workers
  4. Mother-to-child transmission (the most common route)

Severity: Can cause severe acute hepatitis and may become chronic, increasing the risk of cirrhosis and liver cancer

Prevention: HBV vaccination. It is given to all newborns and is highly effective in preventing mother-to-child transmission.

Hepatitis C (HCV)

Transmission: Primarily through blood, such as sharing needles or unsafe tattooing/piercing equipment

Severity: High risk of becoming chronic; increased risk of cirrhosis and liver cancer

Treatment: Highly effective oral antiviral medications are now available and can cure the infection.

Prevention: No vaccine yet; avoid direct exposure to risk.

Hepatitis D (HDV)

Transmission: Through blood and occurs only in people already infected with HBV

Severity: Makes hepatitis B much more severe; higher risk of cirrhosis and liver cancer

Prevention: HBV vaccination also protects against HDV.

Hepatitis E (HEV)

Transmission: Eating undercook meat, especially pork or shellfish, or drinking contaminated water

Severity: High fever, body aches, fatigue; usually self-limiting, but can be severe in pregnant women and older adults

Prevention: Good food and water hygiene; eat thoroughly cooked pork. There is currently no widely available vaccine.

Warning Symptoms Not to Ignore

  1. Yellowing of the skin and eyes
  2. Pain in the right upper abdomen
  3. Nausea, vomiting, loss of appetite
  4. Easy fatigue and weakness
  5. Dark urine, pale stools
  6. Unexplained weight loss
  7. Chronic itching of the skin

Who Should Be Screened for Viral Hepatitis?

You should be tested at least once a year if you have any of the following risks:

  1. Abnormal liver function tests
  2. Unprotected sexual activity
  3. Injection drug use or unsafe tattooing/piercing
  4. History of blood transfusion or blood products
  5. Healthcare workers
  6. Pregnant women
  7. Family members with hepatitis B or C

Treatment Approaches for Each Type

Hepatitis A:

There is no specific antiviral treatment. Most patients recover on their own with rest, adequate hydration, and monitoring of liver function. Symptoms usually resolve within weeks to a few months.

Hepatitis B:

Acute infection may resolve spontaneously or require treatment. Chronic infection may require antiviral medications to suppress the virus and reduce liver inflammation. Regular monitoring of liver enzymes and viral load is essential to prevent cirrhosis and liver cancer. Carriers need ongoing follow-up even in the absence of symptoms.

Hepatitis C:

Direct-acting antivirals (DAAs) offer cure rates of over 95%, especially when treatment is initiated early and risk factors are managed. Early detection leads to better outcomes and lowers the risk of cirrhosis and liver cancer.

Hepatitis D:

Must be managed together with hepatitis B, as HDV occurs only in those already infected with HBV. Care should be provided closely by a hepatologist.

Hepatitis E:

Supportive care is similar to that for hepatitis A. In pregnant women, patients with chronic kidney disease, or those with weakened immunity, the disease can be severe and potentially life-threatening.

How to Prevent Viral Hepatitis

  1. Get vaccinated against hepatitis A and B as recommended by your doctor
  2. Practice safe sexual intercourse
  3. Use safe needles and never share them
  4. Eat well-cooked food and drink clean water
  5. Have regular health check-ups

If you have any of these symptoms, consult and make an appointment with a specialist at Vejthani International Hospital.

Frequently Asked Questions About Viral Hepatitis

1. Is viral hepatitis dangerous?

  • Yes. If left untreated, it can progress to cirrhosis and liver cancer, especially hepatitis B and C, which have a high risk of becoming chronic.

2. If there are no symptoms, is testing still necessary?

  • Absolutely. More than 70% of patients have no symptoms in the early stages. The liver can be slowly damaged without you realizing it. A blood test is the most accurate way to detect the infection.

3. How fast can viral hepatitis progress?

  • It depends on the type of virus and each person’s health factors. Hepatitis B and C can lead to cirrhosis within 10–20 years if not properly diagnosed and treated.

4. Who should receive the hepatitis B vaccine?

  • Today, the vaccine is affordable and highly safe. It is recommended for everyone who is not infected with hepatitis B and has no immunity. People at high risk for HBV infection include:
  1. Those with family members who have hepatitis B
  2. Infants born to mothers with hepatitis B
  3. Healthcare workers
  4. Spouses or partners of people with hepatitis B
  5. Patients with chronic kidney failure requiring dialysis
  6. People who inject drugs
  7. Patients who need immunosuppressive therapy

For more information, contact
Gastroenterology and Hepatology Center , Vejthani International Hospital
Tel: 02-734-0000 Ext. 2960, 2961, 2966
English Hotline: (+66)85-223-8888

Medically Reviewed by

DR. SASIPIM JAMIKORN
DR. SASIPIM JAMIKORN

Internal Medicine

Gastroenterology and Hepatology

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