Overview

Preeclampsia is a serious pregnancy condition that typically develop after 20 weeks of pregnancy. People with preeclampsia will experience elevated blood pressure, protein in their urine, swelling of the legs, feet and hands, headaches, impaired vision, and even organ damage.

Treatment for preeclampsia is early delivery. The severity and the current gestational age will determine if when the patient should give birth. Preeclampsia is treated with close monitoring, blood pressure-lowering medicines, and complications management prior to birth.

Preeclampsia can progress to eclampsia, a severe complication that can have health risks for the mother and the unborn baby. Preeclampsia had progressed to eclampsia if the patient is experiencing seizures.

The patient with this condition should be treated by the healthcare professional because the condition could be dangerous or life-threatening for the mother and the unborn baby if left untreated.

Symptoms

Preeclampsia can frequently occur without any symptoms. Preeclampsia signs and symptoms are frequently discovered during standard prenatal checkups with a healthcare professional.

Preeclampsia signs and symptoms may include:

  • Hypertension with blood pressure greater than 140/90 mmHg.
  • Swelling of the extremities
  • Blurred vision, sensitivity to light, or temporary loss of vision
  • Headaches
  • Fluid in the lungs that cause difficulty in breathing
  • Upper abdominal pain, commonly on the right side under the ribs
  • Nausea or vomiting
  • High protein level in the urine (proteinuria)
  • Low platelet count (thrombocytopenia)
  • High liver enzymes

Typically, the gradual weight gain and swelling (edema) are normal during pregnancies. Preeclampsia may be detected by abrupt weight gain or edema, particularly in the hands and face.

Pregnancy-related high blood pressure concerns

  • Preeclampsia: is one type of high blood pressure (hypertension) disorder that can develop during pregnancy.
  • Chronic hypertension: is high blood pressure that occurs or was present before to 20 weeks of pregnancy. Chronic hypertension is the term used to describe high blood pressure that lasts longer than three months after giving birth.
  • Gestational hypertension: is increased blood pressure that appears after 20 weeks without high amounts of protein in the urine. Preeclampsia can manifest in certain pregnant women with gestational hypertension. This condition usually disappears after delivery.
  • Chronic hypertension with superimposed preeclampsia: happens in women who have been previously diagnosed with chronic high blood pressure and experience pregnancy-related health issues such as protein in the urine and/or high blood pressure that worsens.

If the pregnant patient is experiencing any signs and symptoms such as severe headache, visual problems, abdominal pain, or difficulty in breathing, it is recommended to seek medical help.

Particularly if it is the first pregnancy, it can be challenging to determine when the new symptoms are just a normal aspect of being pregnant or they could signify a significant issue. Contact the healthcare professional if the symptoms cause any concern.

Causes

The exact cause of preeclampsia is unknown. Most experts says that preeclampsia maybe caused by placenta that does not function properly. New blood vessels form and grow early in pregnancy to provide the placenta with nourishment and oxygen, however in preeclampsia it may result in a reduction of the blood supply to the placenta, which may cause issues for both the mother and the unborn child.

The mother’s blood pressure may not be properly controlled if there are issues with the placenta’s blood circulation.

Risk factors

Preeclampsia is associated with an increased risk of the following conditions:

  • History: Patient who had been diagnosed with preeclampsia from the previous pregnancy have higher risk to develop another preeclampsia for the next pregnancy.
  • Multiple pregnancy: One or more pregnancy could put risk for preeclampsia. Being pregnant with a new partner could also put risk to the condition to develop.
  • Other diseases: The following preexisting condition could increase the risk of preeclampsia. The following condition are chronic high blood pressure, type 1 or type 2 diabetes before pregnancy, kidney diseases, or autoimmune disorders.

Preeclampsia is moderately put the patient at risk with the following conditions:

  • Age: first pregnancy during teenager age or over 40 years old.
  • Family history: Mother or siblings of the patient had history of preeclampsia during their pregnancy.
  • Race: Some studies say that African-American have higher risk to develop preeclampsia than other women.
  • Weight: Patient have higher risk for preeclampsia if their body mass index is categorized as obese.
  • Pregnancy interval: The patient have risk to develop preeclampsia if their pregnancy interval is less than 2 years or more than 10 years.
  • In-vitro fertilization

Diagnosis

After 20 weeks of pregnancy, if the patient have high blood pressure and at least one of the following signs and symptoms, then they are likely to be diagnosed with preeclampsia.

  • Protein in the urine (proteinuria)
  • Signs of kidney or liver damage
  • Low blood platelet count
  • Fluid in the lungs (pulmonary edema)
  • New headache that does not go away after taking medication
  • Vision disturbances

Healthcare professional will conduct further investigation if the patient have high blood pressure, to assess for any other signs of preeclampsia.

  • Blood tests: Blood test will be recommended to evaluate for any signs of kidney and liver damage and if they are functioning normally. The test could also help assess the platelet count.
  • Urinalysis: Midstream catch or 24-hour urine sample will be ordered by the healthcare professional to evaluate for any kidney damage.
  • Fetal ultrasound: Estimates of the baby’s weight and the amount of fluid in the uterus can be made using the images measures generated during the ultrasound examination. Close monitoring of the growth of the fetus will be recommended by the healthcare professional.
  • Nonstress test or biophysical profile: A nonstress test is a quick process that determines how the baby’s heart rate responds to fetal movement.

An ultrasound is used to measure your baby’s respiration, muscle tone, movement, and amniotic fluid volume during a biophysical profile.

Treatment

Preeclampsia is mostly treated by either giving early birth or managing the condition until the proper time for delivery. If the mother is at 37th week or the fetus had been developed, the healthcare professional will induce labor or may perform cesarean section. If the fetus had not developed properly then the treatment will be based on the symptoms of mild preeclampsia until the baby had properly developed for safe delivery.

If the preeclampsia is mild, the healthcare professional may schedule the patient frequently to check on their blood pressure, any changes in the signs or symptoms, and the wellbeing of the unborn child. A daily blood pressure check at home will probably be required for the patient.

If patient have severe preeclampsia then they are required to be admitted at the hospital for monitoring blood pressure and complications that may arise. The development and general health of the infant will be frequently evaluated by the healthcare professional. If the patient have severe preeclampsia, depending on the severity of the problem and the baby’s health and readiness, the doctor may recommend the delivery of the baby before 37 weeks.

The following drugs are frequently used to treat severe preeclampsia:

  • Antihypertensive drugs: Medications that lower the blood pressure.
  • Anticonvulsant medication: Medications that prevent seizure such as magnesium sulfate.
  • Corticosteroids: Medication that promote the development of the baby’s lung prior to delivery.

After giving birth, patients need to be constantly monitoring for any high blood pressure and other preeclampsia symptoms. They will be instructed before they could leave the hospital, when to call an ambulance if they get postpartum preeclampsia symptoms such severe headaches, vision problems, severe abdominal pain, nausea, or vomiting.

Doctors who treat this condition