Malignant peripheral nerve sheath tumors are the tumors that form in the lining of the nerves that extend from the spinal cord into the body. It can be found in any part of the body, especially the deep tissue of the arms, legs, and trunk. This rare type of cancer can cause the affected area to be painful and weak or have a lump that grows bigger over time.
Surgery is mostly recommended for malignant peripheral nerve sheath tumors, but radiation therapy and chemotherapy can also be alternatives in certain cases.
Signs and symptoms of malignant peripheral nerve sheath tumors include:
In case of persistent signs and symptoms, seeing a doctor is recommended.
Causes of malignant peripheral nerve sheath tumors are still unclear. All that is known for now is that the cancerous cells originate from genetic mutations happening in the protective lining around a nerve. This abnormality causes the affected cells to multiply out of control without dying, unlike normal cells. This leads to accumulations of abnormal cells which form a tumor that can spread to nearby tissue or any other parts of the body.
Contributing factors of malignant peripheral nerve sheath tumors include:
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