Overview
Inflammation of the child’s tissues and organs, such as the heart or joints, is brought on by the rare autoimmune condition known as rheumatic fever. Both strep throat and scarlet fever are bacterial infections that result from an infection with Group A Streptococcus bacteria. The immune system of the child may begin attacking its own tissues if the infections are not treated.
Most frequently, children between the ages of 5 and 15 are affected with rheumatic fever. However, it can also appear in adults and younger children. Heart failure and damaged heart valves are among the long–term effects of rheumatic fever. Treatment can lessen pain, lessen inflammation–related damage, and stop rheumatic fever from returning.
Serious health issues affecting the child’s heart, joints, or other organs may result in serious complications. Take a child to the healthcare provider if it appears they may have strep throat or scarlet fever. This may lessen the risk of rheumatic fever.
Symptoms
People may be affected in various ways by rheumatic fever. Sometimes strep infections are so mild that people are unaware they have them until later when rheumatic fever appears.
Inflammation of the heart, joints, skin, or central nervous system causes the symptoms of rheumatic fever. There could be a few or many symptoms. Throughout the course of the disease, symptoms may change. Rheumatic fever often starts 2 to 4 weeks after contracting strep throat.
Signs and symptoms of rheumatic fever might include:
- Rash: A rash is one of the most common symptoms of rheumatic fever. A flat, red rash with irregular edges is possible.
- Fever
- Tender, swollen, and painful joints, especially in the knees, ankles, elbows, and wrists.
- Nodules or tiny bumps under the child’s skin
- The pain originating in one joint and subsequently shifting to another joint.
- Chest pain and abnormal heartbeat
- Fatigue
- Heart murmur
- Syndeham chorea, which causes jerky, uncontrollable movements of the hands, feet, and face.
- Abnormal behavioral outbursts, such as sobbing or inappropriate laughter, accompany Sydenham chorea.
- Persistent or unexplained headaches, particularly if the child has never previously reported having head pain.
Rheumatic fever can be prevented with proper strep throat treatment. If the child has a sudden sore throat, swallowing trouble, fever, headache, stomach pain, nausea, or vomiting, then schedule an appointment with the healthcare provider.
Causes
When a child has rheumatic fever, their immune system overreacts and starts attacking healthy tissues, specifically in the heart, joints, skin, and central nervous system. Tissue swelling (inflammation) is the result of this immune system overreaction. This overreaction may be brought on by untreated scarlet fever or strep throat. It occurs when group A Streptococcus infections in children are not treated with antibiotics. When the immune system’s antibodies initiate a response, there is a possibility that the reaction may inadvertently harm healthy tissues and organs instead of solely targeting the bacteria.
When strep throat is promptly treated with antibiotics and all medicine is taken as directed, there is a small chance that rheumatic fever will develop. If a child experiences one or multiple untreated episodes of strep throat or scarlet fever, it can lead to the development of rheumatic fever.
Risk factors
Rheumatic fever may be brought on by a number of factors, including:
- Age: Rheumatic fever may affect anybody. But children and teenagers (aged 5 to 15) are the ones who are most affected. Rheumatic fever in adults is quite rare.
- Family history: Family members may be more susceptible to contracting rheumatic fever if one member has already experienced it. Some persons may be predisposed to developing rheumatic fever due to one or more genes.
- Environmental factor: Overcrowding, poor sanitation, and other factors that can let strep bacteria easily spread among numerous individuals are linked to a higher risk of rheumatic fever. Most rheumatic fever patients resides in areas with few medical resources, such as underdeveloped nations. The child may also be at risk if they reside in an area where getting medication or medical attention is challenging.
- Specific type of strep bacteria: Rheumatic fever is more likely to be caused by specific strep bacteria strains than by other strains.
- Health: The danger may increase in children who have compromised immune systems. Rheumatic fever may be more likely to strike children who frequently contract strep infections.
Diagnosis
Rheumatic fever cannot be diagnosed with a single test. Rheumatic fever is diagnosed based on medical history, a physical examination, and certain test results. Rheumatic fever tests may involve the following:
- Blood tests: Blood tests can be used to look for indicators (markers) of inflammation. The erythrocyte sedimentation rate and C–reactive protein are among these tests. Blood can be tested to see if there are any strep bacteria antibodies present. The actual bacteria may no longer be found in the blood or tissues of the throat.
- Electrocardiogram (ECG or EKG): Heart electrical activity is monitored during this test. It may help in the diagnosis of irregular heartbeats and assist a healthcare provider in figuring out whether any areas of the heart might be enlarged.
- Echocardiogram: Pictures of the beating heart are made using sound waves. An echocardiography demonstrates how the heart and heart valves function.
Jones criteria: The Jones criteria may occasionally be used by healthcare providers to identify rheumatic fever. The child must meet two major criteria, or one major and two minor criteria, from the following lists in order to be diagnosed with rheumatic fever. Additionally, there needs to be experimental proof of an earlier infection with group A streptococcus.
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- Major criteria:
- Arthritis of several joints.
- Heart inflammation (carditis).
- Bumps (nodules) under their skin.
- Rapid, jerky movements (chorea).
- Skin rash (erythema marginatum).
- Minor criteria:
- Fever.
- Elevated erythrocyte sedimentation rate (ESR) or C–reactive protein (CRP) levels.
- Arthralgia (joint pain).
- EKG (electrocardiogram) changes.
- History of previous rheumatic fever or rheumatic heart disease.
- Major criteria:
Treatment
The goals of rheumatic fever treatment is to treat the infection at first, followed by symptom relief, inflammation management, and relapse prevention. Rheumatic fever treatment options include:
- Antibiotics: For the treatment of the underlying bacterial infection, healthcare providers prescribe antibiotics such as penicillin or another antibiotic.
- To prevent a recurrence of rheumatic fever, a healthcare provider often prescribes another course of antibiotics after the initial course has been completely completed. Preventive care will probably last until the child reaches age 21 or has finished a minimum five-year course of treatment, whichever is longer. People who have cardiac inflammation during rheumatic fever may require 10 years or more of prophylactic antibiotic therapy.
- Anti–inflammatory medication: A combination of aspirin and naproxen may be used to treat pain, fever, and inflammation. Additionally, this medicine may help with symptoms including pain in the joints.
- Corticosteroid may be recommended if the symptoms are severe or if the child fails to improve after using anti-inflammatory medications.
- Antiseizure drugs: The involuntary movements brought on by Sydenham chorea may be treated with medicines like valproic acid or carbamazepine.
- Long–term care: How the child will be treated for rheumatic fever in the long run should be discussed with the healthcare provider. Rheumatic heart disease, which is caused by rheumatic fever, may take years or even decades to manifest. Always disclose any prior rheumatic fever to the healthcare provider.
