Overview

Measles, a childhood illness caused by a virus, was once widespread, is now largely preventable through vaccination.
Measles is identifiable by a unique red, blotchy rash that usually begins on the face and behind the ears, then spreads downward to the chest, back, and eventually to the feet. Also known as rubeola, measles is highly contagious and poses serious risks, including death, especially for young children. Although mortality rates have decreased globally due to higher measles vaccination rates among children, the disease still claims over 200,000 lives each year, with children being the most vulnerable.

Symptoms

Measles symptoms manifest approximately 10 to 14 days following exposure to the virus. Common signs and symptoms of measles include:

  • Fever
  • Runny nose
  • Sore throat
  • Dry cough
  • Conjunctivitis (eye inflammation)
  • Koplik’s spots, which are tiny white dots with bluish-white centers on a red background that are located inside the mouth on the inner lining of the cheek
  • A rash on the skin composed of large, flat blotches that frequently merge together

The infection progresses through stages over a period of 2 to 3 weeks.

  • Infection and incubation. During the initial 10 to 14 days post-infection, the measles virus proliferates within the body without exhibiting any signs or symptoms of the illness.
  • Nonspecific signs and symptoms. Typically, measles begins with a mild to moderate fever, often accompanied by a persistent cough, a runny nose, irritated eyes (conjunctivitis), and a sore throat. This initial phase of relatively mild symptoms may endure for 2 to 3 days.
  • Acute illness and rash. The rash consists of small red spots, some of which are slightly raised. These spots and bumps appear in close clusters, resulting in a blotchy red appearance of the skin. The rash typically begins on the face. In the subsequent days, the rash extends downwards over the arms, chest, and back, and further down to the thighs, lower legs, and feet. Simultaneously, the fever escalates dramatically, frequently reaching temperatures as high as 104 to 105.8 F (40 to 41 C).
  • Recovery. The measles rash typically persists for approximately seven days. It diminishes gradually, starting from the face and concluding on the thighs and feet. Even after other symptoms of the illness subside, the cough and darkening or peeling of the affected skin may persist for about 10 days.

A person infected with measles can spread the virus to others for about eight days, starting four days before the rash appears and ending four days after the rash appears.

If you suspect you or your child have been exposed to measles, or if you notice a rash similar to measles, it’s important to contact your doctor. It’s also advisable to review your family’s vaccination records with your doctor, especially before your children start daycare, school, or college, and before any international travel outside your country.

Causes

Measles is an extremely contagious disease, easily transmitted from one person to another. It originates from a virus found in the nose and throat of an infected individual, whether they are a child or an adult. When someone with measles coughs, sneezes, or talks, tiny infectious droplets are released into the air. These droplets can be inhaled by others and remain airborne for up to an hour. Furthermore, these infectious droplets can settle on surfaces, where the virus can survive and spread for several hours. You can become infected with the measles virus by touching a contaminated surface and then touching your mouth, nose, or eyes.

Measles is highly contagious from approximately four days before the rash appears to four days after. Around 90% of individuals who have not had measles before or have not been vaccinated are susceptible to contracting the virus when exposed to an infected person.

Risk factors

Factors that increase the risk of measles comprise:

  • Lacking a vaccination. You have a far higher chance of contracting the measles if you have not received the vaccination.
  • Going abroad on travel. You run a larger risk of contracting measles if you visit nations where the illness is more widespread.
  • Being deficient in vitamin A. You run the risk of experiencing more severe measles symptoms and complications if your diet is deficient in vitamin A.

Diagnosis

Your doctor can typically diagnose measles by observing the characteristic rash along with a small, bluish-white spot on a bright red background known as Koplik’s spot, which appears inside the cheek.

During the examination, your doctor may ask about your or your child’s measles vaccination status, recent international travel, and potential exposure to individuals with rash or fever.

However, since many doctors may not have encountered measles and considering that the rash resembles other illnesses, further diagnostic tests may be necessary. If needed, a blood test can confirm the presence of measles. Additionally, the measles virus can be identified through a throat swab or urine sample.

Treatment

Once someone contracts measles, there is no specific treatment available. Management primarily centers around providing comfort measures to alleviate symptoms, such as rest, and addressing or preventing potential complications.
However, steps can be taken to prevent individuals lacking immunity to measles after exposure to the virus.

  • Post-exposure vaccination. Individuals lacking immunity to measles, including infants, may receive the measles vaccine within 72 hours of exposure to the virus to establish protection against it. In cases where measles still develops, symptoms are typically milder and of shorter duration.
  • Immune serum globulin. Pregnant women, infants, and individuals with weakened immune systems who are exposed to the virus may be administered an injection of immune serum globulin, which contains proteins (antibodies). When administered within six days of exposure to the virus, these antibodies can either prevent measles or mitigate the severity of symptoms.

Medications

Management for a measles infection may involve:

  • Medication to relieve fever. If fever is causing discomfort for you or your child during a measles infection, you can utilize over-the-counter medications like acetaminophen, ibuprofen, or naproxen sodium to help reduce the fever. Ensure to carefully read the labels or consult your doctor or pharmacist for the appropriate dosage. It’s important to be cautious when giving aspirin to children or teenagers. Although aspirin is deemed safe for children aged 3 and older, it should never be given to children or teenagers recuperating from chickenpox or flu-like symptoms. This precaution is essential as aspirin has been associated with Reye’s syndrome, a rare yet potentially life-threatening condition, in such individuals.
  • Antibiotics. Should a bacterial infection such as pneumonia or an ear infection emerge during a measles episode, your doctor may prescribe an antibiotic.
  • Vitamin A. Children with deficient levels of vitamin A are prone to experiencing a more severe form of measles. Supplementing a child with vitamin A can help mitigate the severity of the infection. Typically, it is administered as a large dose of 200,000 International Units (IU) for children aged over one year. Younger children may receive smaller doses.

Doctors who treat this condition